https://nova.newcastle.edu.au/vital/access/ /manager/Index en-au 5 Arachidonic acid supplementation modulates blood and skeletal muscle lipid profile with no effect on basal inflammation in resistance exercise trained men https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:48964 Thu 20 Apr 2023 09:41:49 AEST ]]> Inhibition of platelet aggregation by omega-3 polyunsaturated fatty acids is gender specific: redefining platelet response to fish oils https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:7759 Sat 24 Mar 2018 08:41:54 AEDT ]]> Dietary supplementation with docosahexaenoic acid rich fish oil increases circulating levels of testosterone in overweight and obese men https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:39180 n = 29/32) were included in the current analysis (male: n = 22, 36.07%). DHA-enriched fish oil supplementation increased total testosterone levels in males after adjusting for baseline levels, age and BMI. There was no treatment effect in females. Changes in testosterone levels in males were positively associated with changes to omega-3 PUFAs EPA and DHA and inversely correlated with omega-6 PUFA, arachidonic acid and dihomo-gamma-linolenic acid content in erythrocyte membranes, and was associated with beneficial changes to fasting insulin and HOMA-IR across the course of the study. DHA-enriched fish oil supplementation increases testosterone levels in overweight and obese men. Further research is warranted to substantiate these findings with a larger sample size and a longer follow-up period.]]> Mon 23 May 2022 16:16:26 AEST ]]> DHA-enriched fish oil reduces insulin resistance in overweight and obese adults https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:39169 n = 38) or 2 g corn oil (CO) /day (control, n = 35) for 12 weeks in a double-blind randomised controlled trial. A fasting blood sample was collected at 0 and 12 weeks for assessment of IR, glucose and blood lipid profile. Sixty-eight participants completed the intervention. Compared with CO (n = 32), FO (n = 36) significantly reduced fasting insulin by -1.62 μIU/L (95%CI: -2.99, -0.26,) (p = 0.021) and HOMA-IR by -0.40 units (95%CI: -0.78, -0.02, p = 0.038). Higher insulin and HOMA-IR at baseline were associated with greater reductions in the FO group (p < 0.001). There was no interaction between sex and treatment for the change in insulin (p-interactionsex*treatment = 0.816) or HOMA-IR (p-interactionsex*treatment = 0.825). DHA-enriched FO reduces IR in adults with abdominal obesity, however, sex-dependent differences were not evident in this study.]]> Fri 20 May 2022 16:31:18 AEST ]]>